Orthosiphon stamineus Proteins Alleviate Pentylenetetrazol-Induced Seizures in Zebrafish
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چکیده
منابع مشابه
Orthosiphon stamineus Leaf Extract Affects TNF-α and Seizures in a Zebrafish Model
Epileptic seizures result from abnormal brain activity and can affect motor, autonomic and sensory function; as well as, memory, cognition, behavior, or emotional state. Effective anti-epileptic drugs (AEDs) are available but have tolerability issues due to their side effects. The Malaysian herb Orthosiphon stamineus, is a traditional epilepsy remedy and possesses anti-inflammatory, anti-oxidan...
متن کاملEffect of berberine on pentylenetetrazol-induced seizures in rats
Objective: Antiepileptic drugs (AEDs) that are usually used for treatment of epilepsy have substantial side effects and about 30% of patients continue to have seizures with current AEDs therapy. Some herbs which traditionally used in the management of seizures of many rural areas of the developing countries have shown anticonvulsant activity in modern pharmacological bioassays. The aim of the p...
متن کاملMontelukast Inhibits Pentylenetetrazol-Induced Seizures in Rats
BACKGROUND Montelukast is an antiinflammatory drug with an antioxidant property. In this study, we aimed to reveal whether montelukast has a preventive effect against seizures and post-seizure oxidative stress in pentylenetetrazol (PTZ)-induced seizures in rats. MATERIAL AND METHODS Of the 48 male Sprague-Dawley rats used in the study, 24 were assigned to EEG recordings (group A) and 24 were ...
متن کاملMedicinal Potentials Of Orthosiphon Stamineus Benth
Orthosiphon stamineus Benth. is a medicinal herb belonging to the family Lamiaceae, grown in Southeast Asia. Leaves of this plant are used commonly in Southeast Asia and European countries for herbal tea, well known as “Java tea”. Traditionally leaves of this plant have been used as diuretic, and to treat rheumatism, abdominal pain, kidney and bladder inflammation, edema and gout. Studies have ...
متن کاملUltrasound-assisted extraction of antioxidants in Misai Kucing (Orthosiphon stamineus).
Ultrasound-assisted extraction (UAE) with ethanol was used to extract the compounds responsible for the antioxidant activities of Misai Kucing (Orthosiphon stamineus). Response surface methodology (RSM) was used to optimize four independent variables: ethanol concentration (%), amplitude (%), duty cycle (W/s) and extraction time (min). Antioxidant compounds were determined by total phenolic con...
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ژورنال
عنوان ژورنال: Biomedicines
سال: 2020
ISSN: 2227-9059
DOI: 10.3390/biomedicines8070191